FDA product approval
not established. No US therapeutic product approval is established by this curated source set; other countries and products may differ.
Metabolic · compound · checked 2026-10-09
MOTS-C
MOTS-c is a peptide made in mitochondria. Papers look at how cells and animals handle metabolic stress. Human work is limited and mostly observational. This source set has no FDA-approved MOTS-c drug. Listed seller sizes here are 5 mg and 10 mg.
Last checked Oct 9, 2026 by PepBear. Not medical advice.
- FDA product
- not established
- Compounding
- not established
- Research
- investigational
- Sport
- prohibited
What is MOTS-C?
The name is a library listing for research vials. Some blends pair MOTS-c with humanin on a separate card. A blend is not two finished clinical programs. The mechanism language is mitochondrial and metabolic. It is not a fat-loss verdict.
Mitochondrial-derived peptide studied in metabolic signaling.
Regulatory status, dated 2026-10-09
Compounding
not established. Compounded products do not carry FDA product approval; legal eligibility is not established here.
Research
investigational. Human therapeutic outcomes are not established in this catalog.
Sport
prohibited. WADA S4 lists MOTS-c.
What the cited papers actually measured
Lee et al. (PMID 25738459) introduced MOTS-c in metabolic-regulation models. Later human and review papers (including PMID 33473109) discuss exercise and aging. Those data are not product approval. They do not test research-market vials. Sport status is unverified on the catalog card.
We mark the cited papers as D. That is our label for how strong those papers are. It does not say the compound works.
How long it lasts, how you store it, listed sizes
The catalog does not record a single hour value. No verified formulation-specific human estimate in this source set; no guessed value is supplied.
Listed sizes are 5 mg and 10 mg. Use the vial label. This page does not invent a mix liquid or a throw-away date.
U-100 math for listed MOTS-C sizes. Each cell is micrograms per syringe mark if you add that much liquid. The table does the same math as the calculator. It does not pick an amount for you.
| Listed vial | 1 mL liquid | 2 mL liquid | 3 mL liquid |
|---|---|---|---|
| 5 mg | 50 | 25 | 16.7 |
| 10 mg | 100 | 50 | 33.3 |
Risks and mix-ups already on the record
- Safety is incomplete; absence of reports does not establish safety.
- Unknown or incomplete for research formulations; this is not a clearance for use.
- Unknown or incomplete; do not infer compatibility with medications or other substances.
People using PepBear often log: Existing clinician-directed records, symptoms and dated health measurements. Record missing data; trends do not demonstrate causation.
Sources
- Primary evidence or regulator source · checked 2026-10-09
- WADA prohibited list · checked 2026-10-09
- MOTS-c paper (PubMed 25738459) · checked 2026-10-09
- MOTS-c review (PubMed 33473109) · checked 2026-10-09
Questions people ask
Does limited human data mean MOTS-c does nothing?
Sparse trials do not prove “no effect.” They also do not prove a reliable effect in people buying research vials. The catalog keeps those as separate questions.
Is the MOTS-c / humanin blend covered here?
The blend has its own card. This calculator uses MOTS-c-only listed sizes.
Related cards
A licensed clinician must interpret the evidence for your situation. This entry provides education, not treatment instructions. Not medical advice. PepBear does not pick a dose, a cycle, or a seller.